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Advances in Patient-Specific Induced Pluripotent Stem Cells Shed Light on Drug Discovery for Amyotrophic Lateral Sclerosis.

Cell transplantation - 1 Sept 2018

Lee Jui-Hao, Liu Jen-Wei, Lin Shinn-Zong, Harn Horng-Jyh, Chiou Tzyy-Wen

Abstract excerpt

Induced pluripotent stem cells (iPSCs), which are generated through reprogramming adult somatic cells by expressing specific transcription factors, can differentiate into derivatives of the three embryonic germ layers and accelerate rapid advances in stem cell research. Neurological diseases such as amyotrophic lateral sclerosis (ALS) have benefited enormously from iPSC technology. This approach can be...

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Identifiers

PMID: 30033758
DOI: 10.1177/0963689718785154
PMCID: PMC6168987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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