Article
Induced Pluripotent Stem Cells and Their Applications in Amyotrophic Lateral Sclerosis
22 Mar 2023
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that results in the loss of motor function in the central nervous system (CNS) and ultimately death. The mechanisms underlying ALS pathogenesis have not yet been fully elucidated, and ALS cannot be treated effectively. Most studies have applied animal or single-gene intervention cell lines as ALS disease models, but they cannot...
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