Article
Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct.
Experimental dermatology - 1 Apr 2019
Swanson Jacob B, Vagnozzi Alicia N, Veniaminova Natalia A, Wong Sunny Y
Abstract excerpt
The uppermost aspect of the hair follicle, known as the infundibulum or hair canal, provides a passageway for hair shaft egress and sebum secretion. Recent studies have indicated that the infundibulum and sebaceous ducts are lined by molecularly distinct differentiated cells expressing markers including Keratin 79 and Gata6. Here, we ablated Gata6 from the skin and observed dilation of both the hair canal and...
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