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Article

In silico prediction of novel residues involved in amyloid primary nucleation of human I56T and D67H lysozyme.

BMC structural biology - 20 Jul 2018

Griffin Jeddidiah W D, Bradshaw Patrick C

Abstract excerpt

BACKGROUND: Amyloidogenic proteins are most often associated with neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, but there are more than two dozen human proteins known to form amyloid fibrils associated with disease. Lysozyme is an antimicrobial protein that is used as a general model to study amyloid fibril formation. Studies aimed at elucidating the...

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Identifiers

PMID: 30029603
DOI: 10.1186/s12900-018-0088-1
PMCID: PMC6053722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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