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Article

Identification of dynamic undifferentiated cell states within the male germline

13 Jul 2018

Abstract excerpt

Abstract The role of stem cells in tissue maintenance is appreciated and hierarchical models of stem cell self-renewal and differentiation often proposed. Stem cell activity in the male germline is restricted to undifferentiated A-type spermatogonia (Aundiff); however, only a fraction of this population act as stem cells in undisturbed testis and Aundiff hierarchy remains contentious. Through newly developed...

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PMID: 30026551
DOI: 10.1038/s41467-018-04827-z

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