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Article

PAX7 expression defines germline stem cells in the adult testis

17 Aug 2014

Abstract excerpt

Spermatogenesis is a complex, multistep process that maintains male fertility and is sustained by rare germline stem cells. Spermatogenic progression begins with spermatogonia, populations of which express distinct markers. The identity of the spermatogonial stem cell population in the undisturbed testis is controversial due to a lack of reliable and specific markers. Here we identified the transcription factor...

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PMID: 25133429
DOI: 10.1172/jci75943

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