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Transfusing children with sickle cell disease using blood group genotyping when the pool of Black donors is limited.

Transfusion - 1 Apr 2024

Leiva-Torres Gabriel André, Cigna Maude, Constanzo-Yanez Jessica, St-Louis Maryse, Perreault Josée, Lavoie Josée, Laflamme Geneviève, Lewin Antoine, Pastore Yves, Robitaille Nancy

Abstract excerpt

BACKGROUND: Red blood cell transfusion is an effective treatment for patients with sickle cell disease (SCD). Alloimmunization can occur after a single transfusion, limiting further usage of blood transfusion. It is recommended to match for the ABO, D, C, E, and K antigens to reduce risks of alloimmunization. However, availability of compatible blood units can be challenging for blood providers with a limited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38497419
DOI: 10.1111/trf.17778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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