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Article

Fc receptor-like 3 (-169T>C) polymorphism increases the risk of tendinopathy in volleyball athletes: a case control study.

BMC medical genetics - 18 Jul 2018

Salles José Inácio, Lopes Lucas Rafael, Duarte Maria Eugenia Leite, Morrissey Dylan, Martins Marilena Bezerra, Machado Daniel Escorsim, Guimarães João Antonio Matheus, Perini Jamila Alessandra

Abstract excerpt

BACKGROUND: Tendinopathy pathogenesis is associated with inflammation. Regulatory T (Treg) cells contribute to early tissue repair through an anti-inflammatory action, with the forkhead box P3 (FOXP3) transcription factor being essential for Treg function, and the FC-receptor-like 3 (FCRL3) possibly negatively regulating Treg function. FCRL3 -169T>C and FOXP3 -2383C>T polymorphisms are located near elements that...

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Identifiers

PMID: 30021560
DOI: 10.1186/s12881-018-0633-6
PMCID: PMC6052601

Genes

FCRL3
FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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