Article
Association of the matrix metalloproteinase 3 (MMP3) single nucleotide polymorphisms with tendinopathies: case-control study in high-level athletes.
International orthopaedics - 1 May 2021
Briški Nina, Vrgoč Goran, Knjaz Damir, Janković Saša, Ivković Alan, Pećina Marko, Lauc Gordan
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMPs) play an important role in matrix remodelling, as well as in tendon integrity. Due to overuse, athletes often develop chronic tendinopathies. If not treated, they lead to severe impairment, even complete tendon ruptures. AIM: The main purpose of this study was to investigate whether three functional polymorphisms within the MMP3 gene are associated with increased risk...
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