Article
Redirection of Metabolism in Response to Fatty Acid Kinase in Staphylococcus aureus.
Journal of bacteriology - 1 Oct 2018
DeMars Zachary, Bose Jeffrey L
Abstract excerpt
Staphylococcus aureus is capable of phosphorylating exogenous fatty acids for incorporation into the bacterium's membrane via the fatty acid kinase, FakA. Additionally, FakA plays a significant role in virulence factor regulation and skin infections. We previously showed that a fakA mutant displays altered growth kinetics in vitro, observed during the late-exponential phase of growth. Here, we demonstrate that...
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