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Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase

23 Oct 2024

Abstract excerpt

Gram-positive bacteria utilize a Fatty Acid Kinase (FAK) complex to harvest fatty acids from the environment. This complex consists of the fatty acid kinase, FakA, and an acyl carrier protein, FakB, and is known to impact virulence and disease outcomes. Despite some recent studies, there remain many outstanding questions as to the enzymatic mechanism and structure of FAK. To better address this knowledge gap, we...

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PMID: 39454961
DOI: 10.1016/j.jbc.2024.107920

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