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Article

A Tandem Liquid Chromatography-Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus.

Journal of visualized experiments : JoVE - 28 Mar 2017

Samuels David J, Wang Zhe, Rhee Kyu Y, Brinsmade Shaun R

Abstract excerpt

In an effort to thwart bacterial pathogens, hosts often limit the availability of nutrients at the site of infection. This limitation can alter the abundances of key metabolites to which regulatory factors respond, adjusting cellular metabolism. In recent years, a number of proteins and RNA have emerged as important regulators of virulence gene expression. For example, the CodY protein responds to levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28448019
DOI: 10.3791/55558
PMCID: PMC5564428

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