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Article

In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury.

Aging cell - 1 Oct 2018

Patsalos Andreas, Simandi Zoltan, Hays Tristan T, Peloquin Matthew, Hajian Matine, Restrepo Isabella, Coen Paul M, Russell Alan J, Nagy Laszlo

Abstract excerpt

Tissue regeneration is a highly coordinated process with sequential events including immune cell infiltration, clearance of damaged tissues, and immune-supported regrowth of the tissue. Aging has a well-documented negative impact on this process globally; however, whether changes in immune cells per se are contributing to the decline in the body's ability to regenerate tissues with aging is not clearly...

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Identifiers

PMID: 30003692
DOI: 10.1111/acel.12815
PMCID: PMC6156497

Genes

GDF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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