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Article

Functional genetic discovery of enzymes using full-scan mass spectrometry metabolomics 1.

Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Feb 2019

Caudy Amy A, Hanchard Julia A, Hsieh Alan, Shaan Saravannan, Rosebrock Adam P

Abstract excerpt

Our understanding of metabolic networks is incomplete, and new enzymatic activities await discovery in well-studied organisms. Mass spectrometric measurement of cellular metabolites reveals compounds inside cells that are unexplained by current maps of metabolic reactions, and existing computational models are unable to account for all activities observed within cells. Additional large-scale genetic and...

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PMID: 30001498
DOI: 10.1139/bcb-2018-0058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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