Article
Novel Contribution of Long Non-coding RNA MEG3 Genotype to Prediction of Childhood Leukemia Risk.
Cancer genomics & proteomics - 1 Jan 2000
Pei Jen-Sheng, Chang Wen-Shin, Chen Chao-Chun, Mong Mei-Chin, Hsu Shih-Wei, Hsu Pei-Chen, Hsu Yuan-Nian, Wang Yun-Chi, Tsai Chia-Wen, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: Acute lymphoblastic leukemia (ALL) is frequent among children. Few studies have researched the relationship between maternally expressed gene 3 (MEG3) and cancer risk. We hypothesized long non-coding RNA MEG3 polymorphisms might influence the risk of childhood ALL. MATERIALS AND METHODS: In a total of 266 patients with childhood ALL and 266 healthy controls, genotypes of MEG3 rs7158663, rs3087918,...
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