Article
CYP2D6 genotype analysis of a Thai population: platform comparison.
Pharmacogenomics - 1 Aug 2018
Chamnanphon Monpat, Gaedigk Andrea, Vanwong Natchaya, Nuntamool Nopphadol, Hongkaew Yaowaluck, Puangpetch Apichaya, Sukasem Chonlaphat
Abstract excerpt
The highly polymorphic CYP2D6 gene locus leads to a wide range of enzyme activity. Since there are limited data for Thai, the major aim was to investigate CYP2D6 genetic variation in a large Thai population (n = 920). CYP2D6 genotyping was performed using four different platforms. Genotype call rates of the Luminex xTAG® and AmpliChip CYP450 test were 96.5% and 87.4%, respectively. Based on Luminex xTAG® data,...
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