Article
Identification of susceptibility gene associated with female primary Sjögren's syndrome in Han Chinese by genome-wide association study.
Human genetics - 1 Nov 2016
Song I-Wen, Chen Hsiang-Cheng, Lin Yuh-Feng, Yang Jenn-Hwai, Chang Chi-Ching, Chou Chung-Tei, Lee Ming-Ta Michael, Chou Yi-Chun, Chen Chien-Hsiun, Chen Yuan-Tsong, Chen Chen-Hung, Wu Jer-Yuarn
Abstract excerpt
Primary Sjögren's syndrome (PSS) is an autoimmune disease targeting exocrine glands. It ten times more dominantly affects women than men with an onset peak at menopause. The genetic factor predisposing women to PSS remains unclear. Therefore, we aimed to identify susceptibility loci for PSS in women. We performed genome-wide association study (GWAS) using 242 female PSS patients and 1444 female control in Han...
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