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Article

An Integrated Framework for Identifying Mutated Driver Pathway and Cancer Progression.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Zhang Wei, Wang Shu-Lin

Abstract excerpt

Next-generation sequencing (NGS) technologies provide amount of somatic mutation data in a large number of patients. The identification of mutated driver pathway and cancer progression from these data is a challenging task because of the heterogeneity of interpatient. In addition, cancer progression at the pathway level has been proved to be more reasonable than at the gene level. In this paper, we introduce an...

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Identifiers

PMID: 29990286
DOI: 10.1109/TCBB.2017.2788016

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