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Article

Efficient methods for identifying mutated driver pathways in cancer.

Bioinformatics (Oxford, England) - 15 Nov 2012

Zhao Junfei, Zhang Shihua, Wu Ling-Yun, Zhang Xiang-Sun

Abstract excerpt

MOTIVATION: The first step for clinical diagnostics, prognostics and targeted therapeutics of cancer is to comprehensively understand its molecular mechanisms. Large-scale cancer genomics projects are providing a large volume of data about genomic, epigenomic and gene expression aberrations in multiple cancer types. One of the remaining challenges is to identify driver mutations, driver genes and driver pathways...

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PMID: 22982574
DOI: 10.1093/bioinformatics/bts564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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