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Article

Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial.

BMC medicine - 10 Jul 2018

Syn Nicholas L, Wong Andrea Li-Ann, Lee Soo-Chin, Teoh Hock-Luen, Yip James Wei Luen, Seet Raymond Cs, Yeo Wee Tiong, Kristanto William, Bee Ping-Chong, Poon L M, Marban Patrick, Wu Tuck Seng, Winther Michael D, Brunham Liam R, Soong Richie, Tai Bee-Choo, Goh Boon-Cher

Abstract excerpt

BACKGROUND: Genotype-guided warfarin dosing has been shown in some randomized trials to improve anticoagulation outcomes in individuals of European ancestry, yet its utility in Asian patients remains unresolved. METHODS: An open-label, non-inferiority, 1:1 randomized trial was conducted at three academic hospitals in South East Asia, involving 322 ethnically diverse patients newly indicated for warfarin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29986700
DOI: 10.1186/s12916-018-1093-8
PMCID: PMC6038204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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