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Article

Subgroup analysis of genotype guided vs traditional warfarin dosing in Asian patients from an open label randomized trial.

Scientific reports - 2 Jan 2026

Wong Hon Jen, Teo Yao Neng, Teo Yao Hao, Syn Nicholas L, Wong Andrea Li-Ann, Teoh Hock-Leun, Seet Raymond C S, Lee Soo-Chin, Goh Boon-Cher, Sia Ching-Hui

Abstract excerpt

Genotype-guided warfarin dosing has shown improved anticoagulation outcomes in individuals of European and Asian ancestry. However, its usefulness in specific subgroups remains uncertain. This open-label, non-inferiority randomized trial (NCT00700895) was conducted across three academic hospitals in Southeast Asia to assess the utility of genotype-guided warfarin dosing in Asian patients, focusing on specific...

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Identifiers

PMID: 41484425
DOI: 10.1038/s41598-025-33831-9
PMCID: PMC12848041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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