Atorvastatin, losartan and captopril may upregulate IL-22 in hypertension and coronary artery disease; the role of gene polymorphism.

doi:10.1016/j.lfs.2018.07.005

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Atorvastatin, losartan and captopril may upregulate IL-22 in hypertension and coronary artery disease; the role of gene polymorphism.

Life sciences - 15 Aug 2018

Akbari Hamed, Asadikaram Gholamreza, Jafari Ahmad, Nazari-Robati Mahdieh, Ebrahimi Ghasem, Ebrahimi Nazanin, Masoumi Mohammad

Abstract excerpt

AIMS: Interleukin-22 (IL-22) may be considered as an important cytokine in maintenance and progression of hypertension and coronary artery disease (CAD). The aim of the present study was to investigate the effect of treatment of hypertension and CAD on serum levels of IL-22 and the possible association of IL-22-rs1179251 gene polymorphism with hypertension and CAD. MATERIALS AND METHODS: A total of 286 subjects...

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PMID: 29981321
DOI: 10.1016/j.lfs.2018.07.005

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