Article
Impact of IL-22 and IL-22 receptor alpha 1 polymorphisms on preeclampsia risk in Chinese Han women.
Journal of cellular biochemistry - 1 Jun 2018
Niu Zhaoyuan, Zhao Xin, Liu Hongling, Quan Jing, Lin Yan, Li Jing, Wang Jingli, Liu Mengchun, Song Weiqing, Chen Aiping, Liu Shiguo
Abstract excerpt
Previous studies have indicated that an increased inflammatory response plays an important role in preeclampsia (PE), and rising levels of interleukin (IL)-22 can trigger inflammation and hyperproliferation, leading to increased production of several pro-inflammatory cytokines such as IL-1, IL-6, and IL-8. We aimed to investigate the association between polymorphisms of IL-22 and IL-22 receptor alpha 1 gene...
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