Article
Effect of rs3910105 in the Synuclein Gene on Dopamine Transporter Availability in Healthy Subjects.
Yonsei medical journal - 1 Aug 2018
Seo Youngduk, Pak Kyoungjune, Nam Hyun Yeol, Seok Ju Won, Lee Myung Jun, Kim Eun Joo, Lee Jae Meen, Kim Seong Jang, Kim In Joo
Abstract excerpt
PURPOSE: The present study investigated associations between dopamine transporter (DAT) availability and α-synuclein levels in cerebrospinal fluid, as well as synuclein gene (SNCA) transcripts, and the effect of single nucleotide polymorphism of SNCA on DAT availability in healthy subjects. MATERIALS AND METHODS: The study population comprised healthy controls who underwent ¹²³I-FP-CIT single-photon emission...
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