Article
Epstein-Barr virus seroreactivity among unaffected individuals within high-risk nasopharyngeal carcinoma families in Taiwan.
International journal of cancer - 10 Aug 2004
Pickard Amy, Chen Chien-Jen, Diehl Scott R, Liu Mei-Ying, Cheng Yu-Juen, Hsu Wan-Lun, Sun Brenda, Hsu Mow-Ming, Chen I-How, Chen Jen-Yang, Yang Czau-Siung, Mittl Beth L, Chou Sheng-Ping, Ruggles Deborah D, Goldstein Alisa M, Hildesheim Allan
Abstract excerpt
Most adults have been infected with EBV. Many studies have indicated that antibodies against specific EBV antigens, particularly IgA antibodies, can be predictive or prognostic of EBV-associated malignancies, such as NPC. We hypothesized that healthy individuals from families with a history of multiple members affected with NPC (who therefore might be genetically susceptible to NPC themselves) might have an EBV...
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