Article
Epstein-Barr Virus-Based Nasopharyngeal Carcinoma (NPC) Risk Prediction Scores Are Elevated in NPC Multiplex Family Members in Taiwan.
The Journal of infectious diseases - 13 Feb 2021
Lee Mei-Hsuan, Huang Yu-Han, Coghill Anna E, Liu Zhiwei, Yu Kelly J, Hsu Wan-Lun, Chien Yin-Chu, Wang Cheng-Ping, Chen Tseng-Cheng, Chen Chien-Jen, Hildesheim Allan
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is caused by Epstein-Barr virus (EBV) and is more likely to occur in susceptible families. Whether genetic susceptibility operates through altered EBV control is incompletely understood. We used a NPC risk prediction model based on 14 EBV markers to compare risk score distribution in unaffected members from multiplex families with that in population-based controls. Despite the...
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