Article
Prognostic utility of anti-EBV antibody testing for defining NPC risk among individuals from high-risk NPC families.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2011
Yu Kelly J, Hsu Wan-Lun, Pfeiffer Ruth M, Chiang Chun-Ju, Wang Cheng-Ping, Lou Pei-Jen, Cheng Yu-Juen, Gravitt Patti, Diehl Scott R, Goldstein Alisa M, Chen Chien-Jen, Hildesheim Allan
Abstract excerpt
PURPOSE: Epstein-Barr virus (EBV) infection and a family history of nasopharyngeal carcinoma (NPC) are associated with NPC risk. We examined the risk associated with EBV markers and their clinical utility to identify NPC susceptibles within high-risk NPC families. EXPERIMENTAL DESIGN: We evaluated antibody titers against viral capsid antigen (VCA) IgA, EBV nuclear antigen-1 (EBNA1) IgA, and DNase among unaffected...
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