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Article

The Combination of JAK2V617F Allele Burden and WT1 Expression can Be Helpful in Distinguishing the Subtype of MPN Patients.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Wu Sanyun, Luo Ping, Rouzi Tuerxunayi, Yu Yalan, Xiong Bei, Wang Yingying, Zuo Xuelan

Abstract excerpt

INTRODUCTION: Classical Philadelphia-negative myeloproliferative neoplasm (MPN) includes Essential Thrombocythemia (ET), Polycythemia Vera (PV) and Primary Myelofibrosis (PMF). The JAK2V617F mutation is part of the major criteria for diagnosis of MPN. WT1 is reported to be highly overexpressed in most hematological malignancy. Our aim was to explore the combination value of JAK2V617F allele burden and WT1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36895113
DOI: 10.1177/10732748231163648
PMCID: PMC10009047

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