Article
JAK2 p.V617F detection and allele burden measurement in peripheral blood and bone marrow aspirates in patients with myeloproliferative neoplasms.
Blood - 28 Nov 2013
Takahashi Koichi, Patel Keyur P, Kantarjian Hagop, Luthra Rajyalakshmi, Pierce Sherry, Cortes Jorge, Verstovsek Srdan
Abstract excerpt
Detection of the JAK2 p.V617F mutation and measurement of its allele burden can be performed using both peripheral blood (PB) and bone marrow (BM) samples from patients with myeloproliferative neoplasms (MPNs). However, the diagnostic accuracy of detecting the JAK2 p.V617F mutation and quantifying its allele burden in PB and BM samples has not been systematically compared. We retrospectively analyzed 388 patients...
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