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Article

Association between polymorphisms of interleukin-17A G197A and interleukin-17F A7488G and risk of colorectal cancer.

Journal of cancer research and therapeutics - 1 Jun 2018

Samiei Golnaz, Yip Wai Kien, Leong Pooi Pooi, Jabar Mohd Faisal, Dusa Noraini Mohd, Mohtarrudin Norhafizah, Seow Heng Fong

Abstract excerpt

BACKGROUND: Interleukin (IL)-17A and IL-17F are inflammatory cytokines mainly produced by T helper 17 cells. IL-17A is known to be protumorigenic while IL-17F has a protective role in cancer. A number of studies have been conducted to determine the association between polymorphisms of IL-17AG197A (rs2275913) and IL-17FA7488G (rs763780) and risk of cancers. No studies have yet to be conducted to genotype the...

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PMID: 29970680
DOI: 10.4103/0973-1482.235345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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