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IL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression

1 Sept 2018

Abstract excerpt

Background: IL-17 expressed by Th17 cells play a crucial role in tissue inflammation by induction of proinflammatory and neutrophil mobilizing cytokines, and IL-17 polymorphisms are associated with colorectal cancer (CRC). Objective: We investigated the expression of IL-17 and the association of IL-17 gene polymorphisms with CRC susceptibility in a Middle East population. Materials and methods: The study included...

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PMID: 30233234
DOI: 10.2147/cmar.s161248

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