Article
Association between polymorphisms in interleukin-17A and interleukin-17F genes and risks of gastric cancer.
International journal of cancer - 1 Jul 2010
Wu Xiaoqin, Zeng Zhirong, Chen Bin, Yu Jun, Xue Ling, Hao Yuantao, Chen Minhu, Sung Joseph J Y, Hu Pinjin
Abstract excerpt
Chronic inflammation is the hallmark of the pathogenesis of Helicobacter pylori-induced gastric cancer. Interleukin (IL)-17A and IL-17F are inflammatory cytokines expressed by a novel subset of CD4+ Th cells and play critical function in inflammation and probably in cancer. We conducted a case-co...
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