Article
Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis.
Human immunology - 1 Jul 2009
Shibata Tomoyuki, Tahara Tomomitsu, Hirata Ichiro, Arisawa Tomiyasu
Abstract excerpt
Interleukin-17A (IL-17A) and IL-17F play a role in tissue inflammation by inducing release of proinflammatory and neutrophil-mobilizing cytokines. We investigated the associations between gastric cancer and polymorphisms of IL-17A (rs2275913, G-197A) and -17F (rs763780, 7488 T/C) genes. The study was performed in 811 subjects (524 without gastric cancer and 287 with gastric cancer). We used the multiplex PCR-SSCP...
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