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Article

A fine-mapping study of central obesity loci incorporating functional annotation and imputation.

European journal of human genetics : EJHG - 1 Sept 2018

Zhang Xiaoyu, Cupples L Adrienne, Liu Ching-Ti

Abstract excerpt

A recent genome-wide association study (GWAS) of central obesity identified 27 loci, from sex-combined analysis, associated with waist-to-hip ratio adjusted for body-mass index (WHRadjBMI) in European-ancestry individuals. Nevertheless, the identified variants may not be the biological causal ones due to the presence of linkage disequilibrium (LD). To better understand the mechanisms underlying the identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29967334
DOI: 10.1038/s41431-018-0168-5
PMCID: PMC6117358

Genes

JUND
DNM3
PIGC
SMAD6

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