Trumpet plots: Visualizing The Relationship Between Allele Frequency And Effect Size In Genetic Association Studies

Abstract excerpt

Recent advances in genome-wide association study (GWAS) and sequencing studies have shown that the genetic architecture of complex diseases and traits involves a combination of rare and common genetic variants, distributed throughout the genome. One way to better understand this architecture is to visualize genetic associations across a wide range of allele frequencies. However, there is currently no standardized...

Topics

Open a Topic to create a Post that cites this publication.

• Algorithms
• Computer Graphics
• Computer Simulation
• Disease
• Genome-Wide Association Study
• Polymorphism, Single Nucleotide
• Software
• User-Computer Interface

Identifiers and source

Literature Corpus work

c1c9555f-1154-550d-af69-8cc578da8310

DOI

10.1101/2023.04.21.23288923