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Article

TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma.

International journal of molecular medicine - 1 Sept 2018

Svahn Fredrika, Paulsson Johan O, Stenman Adam, Fotouhi Omid, Mu Ninni, Murtha Timothy D, Korah Reju, Carling Tobias, Bäckdahl Martin, Wang Na, Juhlin C Christofer, Larsson Catharina

Abstract excerpt

Telomere maintenance, most commonly achieved by telomerase activation through induction of the telomerase reverse transcriptase (TERT) gene, is required for cell immortalization, a hallmark of cancer. Adrenocortical carcinoma (ACC) is an endocrine tumor for which TERT promoter mutations and telomerase activation have been reported. The present study assessed alterations of the TERT gene locus and telomere length...

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Share to Adrenocortical Carcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29956721
DOI: 10.3892/ijmm.2018.3735

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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