Article
New variable selection strategy for analysis of high-dimensional DNA methylation data.
Journal of bioinformatics and computational biology - 1 Aug 2018
Choi Jiyun, Kim Kipoong, Sun Hokeun
Abstract excerpt
In genetic association studies, regularization methods are often used due to their computational efficiency for analysis of high-dimensional genomic data. DNA methylation data generated from Infinium HumanMethylation450 BeadChip Kit have a group structure where an individual gene consists of multiple Cytosine-phosphate-Guanine (CpG) sites. Consequently, group-based regularization can precisely detect...
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