Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective Efficacy.

Viruses - 27 Jun 2018

Chang Chia-Yu, Hsu Wei-Ting, Chao Yu-Chan, Chang Hui-Wen

Abstract excerpt

A new variant of the porcine epidemic diarrhea virus (PEDV) is an emerging swine disease, killing considerable numbers of neonatal piglets in North America and Asia in recent years. To generate immunogens mimicking the complex spike (S) protein folding with proper posttranslational modification to mount a robust immune response against the highly virulent PEDV, two baculoviruses displaying the full-length S...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Suckling
Share to Baculoviridae
Share to Coronavirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunogenicity, Vaccine

Share to Injections, Intramuscular

Share to Porcine epidemic diarrhea virus

Share to Viral Vaccines

Share to Virus Shedding

Source

Open in PubMed Open full text

Identifiers

PMID: 29954081
DOI: 10.3390/v10070346
PMCID: PMC6071207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective Efficacy.PMID 29954081Read ↗

Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2.Semantic proximity Read ↗

Development and comparison of enzyme-linked immunosorbent assays based on recombinant trimeric full-length and truncated spike proteins for detecting antibodies against porcine epidemic diarrhea virusSemantic proximity Read ↗

Development of a Safe and Effective mRNA Candidate Vaccine Against PEDV G2c Genotype InfectionSemantic proximity Read ↗

Immunogenicity and protective efficacy of recombinant adenovirus expressing a novel genotype G2b PEDV spike protein in protecting newborn piglets against PEDV.Semantic proximity Read ↗

Development of a safe and broad-spectrum attenuated PEDV vaccine candidate by S2 subunit replacementSemantic proximity Read ↗

Isolation and characterization of porcine epidemic diarrhea virus with mutations in the spike gene in China.Semantic proximity Read ↗

Enhancing the virulence of G2a subtype PEDV by chimeric expression of G2c subtype S gene.Semantic proximity Read ↗

Immunodominant and Neutralizing Linear B-Cell Epitopes Spanning the Spike and Membrane Proteins of Porcine Epidemic Diarrhea VirusSemantic proximity Read ↗

A spike-specific whole-porcine antibody isolated from a porcine B cell that neutralizes both genogroup 1 and 2 PEDV strains.Semantic proximity Read ↗

Isolation and characterization of Chinese porcine epidemic diarrhea virus with novel mutations and deletions in the S gene.Semantic proximity Read ↗

N-glycosylation of the PEDV spike protein modulates viral replication and pathogenicitySemantic proximity Read ↗

Modification of N-glycosylation site in the spike protein enhances the neutralizing antibody response against PEDV.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.