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Development of a Safe and Effective mRNA Candidate Vaccine Against PEDV G2c Genotype Infection

4 Sept 2025

Abstract excerpt

Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that causes severe diarrhea, dehydration, and high mortality in piglets, leading to significant economic losses in the swine industry. The spike (S) protein of PEDV is the primary target for neutralizing antibodies and is critical for vaccine development. In this study, the pUC57-S01 and pUC57-S02 plasmids carrying the codon-optimized...

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PMID: 41012638
DOI: 10.3390/v17091210

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