Article
Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2.
Archives of virology - 1 Mar 2016
Wang Xiaobo, Chen Jianfei, Shi Da, Shi Hongyan, Zhang Xin, Yuan Jing, Jiang Shibo, Feng Li
Abstract excerpt
Porcine epidemic diarrhea virus (PEDV) is a coronavirus that infects cells lining the small intestine of swine, resulting in vomiting, diarrhea, and dehydration. The amino acid sequence of the spike (S) protein, which is the principal target recognized by host immune cells, has multiple mutations that distinguish the two PEDV genotypes, G1 and G2. To determine whether these mutations lead to changes in...
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