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Article

A spike-specific whole-porcine antibody isolated from a porcine B cell that neutralizes both genogroup 1 and 2 PEDV strains.

Veterinary microbiology - 1 Jun 2017

Fu Fang, Li Lin, Shan Lingling, Yang Beibei, Shi Hongyan, Zhang Jiaoer, Wang Hongfeng, Feng Li, Liu Pinghuang

Abstract excerpt

Porcine epidemic diarrhea (PED), caused by an alpha coronavirus, is a highly contagious disease and causes high morbidity and mortality in suckling piglets. Isolating PEDV neutralizing antibodies from porcine B cells is critical to elucidate the development of PEDV neutralizing antibodies and the protective mechanism of PEDV infection. Here, we described the isolation of a PEDV-neutralizing antibody from the B...

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Identifiers

PMID: 28622871
DOI: 10.1016/j.vetmic.2017.05.013
PMCID: PMC7117570

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