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Development of a safe and broad-spectrum attenuated PEDV vaccine candidate by S2 subunit replacement

15 Oct 2024

Abstract excerpt

ABSTRACT Porcine epidemic diarrhea (PED) has caused serious economic losses to the swine livestock industry. Due to the rapid variation in the PEDV) genome, especially the spike (S) protein, the cross-protection ability of antibodies between different vaccine strains is weakened. Hence, the rapid development of safe, broad-spectrum and highly effective attenuated PEDV vaccine still needs further research. Here,...

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PMID: 39404450
DOI: 10.1128/jvi.00429-24

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