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Article

The Effect of Balancing Selection on Population Differentiation: A Study with HLA Genes.

G3 (Bethesda, Md.) - 31 Jul 2018

Brandt Débora Y C, César Jônatas, Goudet Jérôme, Meyer Diogo

Abstract excerpt

Balancing selection is defined as a class of selective regimes that maintain polymorphism above what is expected under neutrality. Theory predicts that balancing selection reduces population differentiation, as measured by FST. However, balancing selection regimes in which different sets of alleles are maintained in different populations could increase population differentiation. To tackle the connection between...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29950428
DOI: 10.1534/g3.118.200367
PMCID: PMC6071603

Genes

FST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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