Article
Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
Molecular neurobiology - 1 Feb 2019
Park Min-Jung, Park Hyun-Sun, You Min-Jung, Yoo Jongman, Kim Seung Hyun, Kwon Min-Soo
Abstract excerpt
The functional status of dynamic microglial cells plays an important role in maintaining homeostasis of microenvironment in CNS. In a previous study, we reported that microglia phenotype might be involved in stress vulnerability and depression recurrence. Here, we aimed to clarify a character of microglia exposed persistently to glucocorticoid (GC), which is representative a stress hormone, in primary cultured...
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