Article
Pancreatic cancer as a sentinel for hereditary cancer predisposition.
BMC cancer - 27 Jun 2018
Young Erin L, Thompson Bryony A, Neklason Deborah W, Firpo Matthew A, Werner Theresa, Bell Russell, Berger Justin, Fraser Alison, Gammon Amanda, Koptiuch Cathryn, Kohlmann Wendy K, Neumayer Leigh, Goldgar David E, Mulvihill Sean J, Cannon-Albright Lisa A, Tavtigian Sean V
Abstract excerpt
BACKGROUND: Genes associated with hereditary breast and ovarian cancer (HBOC) and colorectal cancer (CRC) predisposition have been shown to play a role in pancreatic cancer susceptibility. Growing evidence suggests that pancreatic cancer may be useful as a sentinel cancer to identify families that could benefit from HBOC or CRC surveillance, but to date pancreatic cancer is only considered an indication for...
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