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Article

ErbB4 deletion predisposes to development of metabolic syndrome in mice.

American journal of physiology. Endocrinology and metabolism - 1 Oct 2018

Zeng Fenghua, Wang Yinqiu, Kloepfer Lance A, Wang Suwan, Harris Raymond C

Abstract excerpt

ErbB4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between ErbB4 and type 2 diabetes and obesity, but its role in metabolic syndrome (MetS) has not been reported. In the current study we found that mice with ErbB4 deletion developed MetS after 24 wk on a medium-fat diet (MFD), as indicated by development of obesity,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29944391
DOI: 10.1152/ajpendo.00166.2018
PMCID: PMC6230712

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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