Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity

8 Nov 2022

Abstract excerpt

OBJECTIVE: To investigate the potential role of EGFR, ErbBs receptors and neuregulins in human adipose tissue physiology in obesity. METHODS: Gene expression analysis in human subcutaneous (SAT) and visceral (VAT) adipose tissue in three independent cohorts [two cross-sectional (N = 150, N = 87) and one longitudinal (n = 25)], and in vitro gene knockdown and overexpression experiments were performed. RESULTS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Metabolism, Diabetes, and Cancer
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36411648
DOI: 10.1016/j.biopha.2022.113972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesityPMID 36411648Read ↗

NGR4 and ERBB4 as Promising Diagnostic and Therapeutic Targets for Metabolic DisordersSemantic proximity Read ↗

Mutations of NRG4 Contribute to the Pathogenesis of Nonalcoholic Fatty Liver Disease and Related Metabolic Disorders.Semantic proximity Read ↗

ErbB4 deletion predisposes to development of metabolic syndrome in mice.Semantic proximity Read ↗

A Combined Effect of Expression Levels of Obesity-Related Genes and Clinical Factors on Cancer Survival Rate.Semantic proximity Read ↗

Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose TissueSemantic proximity Read ↗

Downregulation of Exosomal hsa-miR-551b-3p in Obesity and Its Link to Type 2 Diabetes MellitusSemantic proximity Read ↗

Cytoskeletal transgelin 2 contributes to gender‐dependent adipose tissue expandability and immune functionSemantic proximity Read ↗

Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansionSemantic proximity Read ↗

Nrg4 and Gpr120 signalling in brown fatSemantic proximity Read ↗

Fatty acid synthase (FASN), a novel signature for visceral adipose tissues, regulates proliferation, migration and predicts prognosis of clear cell renal cell carcinomaSemantic proximity Read ↗

Obesity impacts the regulation of miR-10b and its targets in primary breast tumorsSemantic proximity Read ↗

Functional Characterization of Obesity-Associated Variants Involving the α and β Isoforms of Human SH2B1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.