Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s

26 Jun 2018

Abstract excerpt

Cytochrome P450 mono-oxygenases (P450) are versatile enzymes which play essential roles in C-source assimilation, secondary metabolism, and in degradations of endo- and exogenous xenobiotics. In humans, several P450 isoforms constitute the largest part of phase I metabolizing enzymes and catalyze oxidation reactions which convert lipophilic xenobiotics, including drugs, to more water soluble species. Recombinant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microbial Natural Products and Biosynthesis
Share to Pharmacogenetics and Drug Metabolism
Share to Steroid Chemistry and Biochemistry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29943426
DOI: 10.1002/bit.26781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450sPMID 29943426Read ↗

<i>Streptomyces</i>cytochromes P450: applications in drug metabolismSemantic proximity Read ↗

Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and functionSemantic proximity Read ↗

Similarities, variations, and evolution of cytochrome P450s in Streptomyces versus MycobacteriumSemantic proximity Read ↗

StreptomycesCytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic AgentsSemantic proximity Read ↗

Functional Analysis of Cytochrome P450s Involved in Streptovaricin Biosynthesis and Generation of Anti-MRSA Analogues.Semantic proximity Read ↗

Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us?Semantic proximity Read ↗

Cytochrome P450 107U1 is required for sporulation and antibiotic production in Streptomyces coelicolor.Semantic proximity Read ↗

Protein engineering of CYP105s for their industrial uses.Semantic proximity Read ↗

Cytochrome P450 biodiversity and biotechnology.Semantic proximity Read ↗

Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megateriumSemantic proximity Read ↗

Exploring the potential of xenobiotic-metabolising enzymes as biocatalysts: evolving designer catalysts from polyfunctional cytochrome P450 enzymes.Semantic proximity Read ↗

[Diversity of P 450: biology and application of diversozyme].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.