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Cytochrome P450 biodiversity and biotechnology.

Biochemical Society transactions - 1 Dec 2006

Kelly S L, Lamb D C, Kelly D E

Abstract excerpt

CYP (cytochrome P450) biodiversity and biotechnology is of importance given the industrial applications and potential for the huge array of genes and proteins that can constitute up to 1% of a coding genome. Historical biotechnological roles for CYPs in mutant fungi diverting the flux of metabolites towards penicillin production, in biotransformations allowing the production of corticosteroids and CYPs as drug...

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PMID: 17073775
DOI: 10.1042/BST0341159

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