An interleukin-10 gene polymorphism associated with the development of cervical lesions in women infected with Human Papillomavirus and using oral contraceptives.

doi:10.1016/j.meegid.2013.06.016

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Article

An interleukin-10 gene polymorphism associated with the development of cervical lesions in women infected with Human Papillomavirus and using oral contraceptives.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2013

Chagas Bárbara Simas, Gurgel Ana Pavla Almeida Diniz, da Cruz Heidi Lacerda Alves, Amaral Carolina Maria Medeiros, Cardoso Marcus Vinicius, Silva Neto Jacinto da Costa, da Silva Luiz Antônio Ferreira, de Albuquerque Eugênia Maria Bezerra, Muniz Maria Tereza Cartaxo, de Freitas Antonio Carlos

Abstract excerpt

Human Papillomavirus (HPV) infection plays a crucial role in the development of cervical lesions and tumors, however most lesions containing high-risk HPVs do not progress to cervical tumors. Some studies suggest that the use of oral contraceptives may increase the risk of cervical carcinogenesis, but this has not been confirmed by all the studies. Cytokines are important molecules that act in the defense of an...

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PMID: 23800422
DOI: 10.1016/j.meegid.2013.06.016

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